Acetazolamide improves loop gain but not the other physiological traits causing obstructive sleep apnoea

Retropharyngeal lipoma causing obstructive sleep apnoea

We present the case of a middle-aged man whose obstructive sleep apnoea (OSA) was caused by a retropharyngeal lipoma, with complete resolution after transoral excision. Lipomas causing OSA are rare, and this represents the seventh reported case in the literature.

Comments on the CrossTalk proposal and opposing view: Elevated loop gain is/loop gain is not a consequence of obstructive sleep apnoea

The issue of whether elevated loop gain is a consequence of obstructive sleep apnoea (OSA) is important and the authors are to be commended for raising it in this CrossTalk proposal (Orr et al. 2014; Younes, 2014). A major aspect of loop gain is the respiratory chemoreflex response and overnight changes were assessed in OSA and non-OSA subjects using rebreathing tests (Duffin, 2011) in the even...

A method for measuring and modeling the physiological traits causing obstructive sleep apnea.

There is not a clinically available technique for measuring the physiological traits causing obstructive sleep apnea (OSA). Therefore, it is often difficult to determine why an individual has OSA or to what extent the various traits contribute to the development of OSA. In this study, we present a noninvasive method for measuring four important physiological traits causing OSA: 1) pharyngeal an...

High-intensity interval training improves obstructive sleep apnoea

Background Three hours per week of vigorous physical activity is found to be associated with reduced odds of sleep-disordered breathing. Aim To investigate whether 12 weeks of high-intensity interval training (HIIT) reduced the apnoea-hypopnea index (AHI) in obese subjects with moderate-to-severe obstructive sleep apnoea. Methods In a prospective randomised controlled exercise study, 30 (bo...

Obstructive Sleep Apnoea Syndrome